Zic3tm2.2Jwb
Targeted Allele Detail
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Symbol: |
Zic3tm2.2Jwb |
Name: |
zinc finger protein of the cerebellum 3; targeted mutation 2.2, John W Belmont |
MGI ID: |
MGI:5470155 |
Synonyms: |
Zic3del |
Gene: |
Zic3 Location: ChrX:57075988-57081990 bp, + strand Genetic Position: ChrX, 32.56 cM
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Alliance: |
Zic3tm2.2Jwb page
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette and left exon 1 floxed. Cre-mediated recombination removed exon 1.
(J:192577)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Zic3 Mutation: |
37 strains or lines available
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Original: |
J:192577 Jiang Z, et al., Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development. Hum Mol Genet. 2013 Mar 1;22(5):879-89 |
All: |
1 reference(s) |
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