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Mthfd1ltm1b(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Mthfd1ltm1b(EUCOMM)Wtsi
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5470152
Synonyms: Mthfd1lz
Gene: Mthfd1l  Location: Chr10:3973118-4167081 bp, + strand  Genetic Position: Chr10, 2.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193285
Parent Cell Line:  JM8A3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mthfd1l Mutation:  53 strains or lines available
References
Original:  J:193285 Momb J, et al., Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):549-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory