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Adcy7tm1.1Pcst
Targeted Allele Detail
Nomenclature
Symbol: Adcy7tm1.1Pcst
Name: adenylate cyclase 7; targeted mutation 1.1, Paul C Sternweis
MGI ID: MGI:5470143
Gene: Adcy7  Location: Chr8:88272403-88329962 bp, + strand  Genetic Position: Chr8, 43.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191067
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 6. An FRT-flanked neo cassette with a 3'loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exon 6 floxed. (J:191067)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy7 Mutation:  1 strain or line available
References
Original:  J:191067 Jiang LI, et al., Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation. Mol Immunol. 2013 May;54(1):14-22
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory