Soat2^tm1.2Llr
Targeted Allele Detail

Summary

• Symbol: Soat2^tm1.2Llr
• Name: sterol O-acyltransferase 2; targeted mutation 1.2, Lawrence L Rudel
• MGI ID: MGI:5469867
• Gene: Soat2 Location: Chr15:102058961-102071904 bp, + strand Genetic Position: Chr15, 57.33 cM
• Alliance: Soat2^tm1.2Llr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT and loxP flanked neo cassette was inserted upstream of exon 11. An additionally loxP site was inserted downstream of exon 13. Enzymatic assay confirmed less than 10% normal activity levels. Flp-mediated recombination removed the neo cassette and left exons 11 through 13 floxed. Cre mediated excision then removed exons 11 through 13. (J:94077, J:184908)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Soat2 Mutation: 37 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)