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Pik3catm1Gne
Targeted Allele Detail
Nomenclature
Symbol: Pik3catm1Gne
Name: phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; targeted mutation 1, Genentech
MGI ID: MGI:5469577
Synonyms: Pik3cae20mwt
Gene: Pik3ca  Location: Chr3:32397671-32466107 bp, + strand  Genetic Position: Chr3, 15.7 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193377
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Single point mutation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3ca Mutation:  14 strains or lines available
References
Original:  J:193377 Yuan W, et al., Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations. Oncogene. 2013 Jan 17;32(3):318-26
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory