Gja1^tm9.2Kwi
Targeted Allele Detail

Summary

• Symbol: Gja1^tm9.2Kwi
• Name: gap junction protein, alpha 1; targeted mutation 9.2, Klaus Willecke
• MGI ID: MGI:5469490
• Synonyms: Cx43^kiECFP
• Gene: Gja1 Location: Chr10:56253297-56266519 bp, + strand Genetic Position: Chr10, 28.64 cM
• Alliance: Gja1^tm9.2Kwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193352
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding sequence. An FRT-flanked neo cassette, loxP site and ECFP were inserted downstream of the open reading frame. Cre-mediated recombination removed the coding sequence and neo cassette. The ECFP remains intact. (J:193352)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gja1 Mutation: 59 strains or lines available

References

• Original: J:193352 Degen J, et al., Dual reporter approaches for identification of Cre efficacy and astrocyte heterogeneity. FASEB J. 2012 Nov;26(11):4576-83
• All: 6 reference(s)