Tg(tetO-Npc1/YFP)1Mps
Transgene Detail

Summary

• Symbol: Tg(tetO-Npc1/YFP)1Mps
• Name: transgene insertion 1, Matthew Scott
• MGI ID: MGI:5468713
• Synonyms: Tg(tetO-Npc1-YFP)
• Transgene: Tg(tetO-Npc1/YFP)1Mps Location: unknown Genetic Position: Chr4, Syntenic
• Alliance: Tg(tetO-Npc1/YFP)1Mps page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Npc1/YFP)1Mps expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Npc1 (MGI:1097712)

• Mutation details: The transgenic vector contains a Npc1-6xHis-YFP-2xFLAG driven by a tet operon-cytomegalovirus minimal promoter (tetO-CMVmin). Line 1 was generated. (J:170312)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:170312 Lopez ME, et al., Anatomically defined neuron-based rescue of neurodegenerative niemann-pick type C disorder. J Neurosci. 2011 Mar 23;31(12):4367-78
• All: 1 reference(s)