Del(1Fcgr2b-Fcgr3)1Vlcg
Allele Detail

Summary

• Symbol: Del(1Fcgr2b-Fcgr3)1Vlcg
• Name: deletion, Chr 1, Regeneron Pharmaceuticals; deletion, Chr 1, Velocigene
• MGI ID: MGI:5468708
• Synonyms: FcgRI-only
• Gene: Del(1Fcgr2b-Fcgr3)1Vlcg Location: Chr1:170788127-170892504 bp Genetic Position: Chr1, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Not Specified
• Mutations: Intergenic deletion, Intragenic deletion
• Del(1Fcgr2b-Fcgr3)1Vlcg involves 13 genes/genome features (Fcgr2b, Gm10522, Fcgr4 ...) View all
• Mutation details: Mice deficient for Fcgr2b, Fcgr3, and Fcgr4 were generated by deletion of the low affinity Fcgr locus using Velocigene technology. (J:190859)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(1Fcgr2b-Fcgr3)1Vlcg Mutation: 0 strains or lines available

References

• Original: J:190859 Albanesi M, et al., Cutting Edge: FcgammaRIII (CD16) and FcgammaRI (CD64) Are Responsible for Anti-Glycoprotein 75 Monoclonal Antibody TA99 Therapy for Experimental Metastatic B16 Melanoma. J Immunol. 2012 Dec 15;189(12):5513-7
• All: 1 reference(s)