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Sox17tm2(EGFP/cre)Mgn
Targeted Allele Detail
Nomenclature
Symbol: Sox17tm2(EGFP/cre)Mgn
Name: SRY (sex determining region Y)-box 17; targeted mutation 2, Mark A Magnuson
MGI ID: MGI:5468103
Synonyms: Sox17.Cre-GFP, Sox17GFPCre
Gene: Sox17  Location: Chr1:4561154-4567577 bp, - strand  Genetic Position: Chr1, 1.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193165
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (RMCE-ready, Recombinase, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsRecombinase-mediated cassette exchange was used to insert exon 3 and a Cre/EGFP (enhanced Green Fluorescent Protein) fusion gene into the loxed cassette allele (LCA) thereby replacing the coding sequence. (J:193165)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox17 (mouse) Summary of all recombinase alleles driven by Sox17.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox17 Mutation:  22 strains or lines available
References
Original:  J:193165 Choi E, et al., Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells. 2012 Oct;30(10):2297-308
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory