Sfxn1^m1Mdf
Spontaneous Allele Detail

Summary

• Symbol: Sfxn1^m1Mdf
• Name: sideroflexin 1; mutation 1, Mark Fleming
• MGI ID: MGI:5468013
• Synonyms: f
• Gene: Sfxn1 Location: Chr13:54225888-54262361 bp, + strand Genetic Position: Chr13, 28.4 cM
• Alliance: Sfxn1^m1Mdf page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: An insertion of a single A residue after codon 15 of the reading frame. This mutation is predicted to result in a truncated protein consisting of the first 15 amino acids followed by 17 novel amino acids before an in-frame stop codon. (J:68377)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sfxn1 Mutation: 40 strains or lines available

Notes

This allele is on of two suggested as responsible for the flexed tail mutation (f). J:128616 suggests that a Smad5 splicing defect (mutation in a polyT element in intron 4) may be causative of flexed tail.

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)