Muc19^tm2.1Culp
Targeted Allele Detail

Summary

• Symbol: Muc19^tm2.1Culp
• Name: mucin 19; targeted mutation 2.1, David Culp
• MGI ID: MGI:5468010
• Gene: Muc19 Location: Chr15:91722531-91832440 bp, + strand Genetic Position: Chr15, 46.14 cM, cytoband E3
• Alliance: Muc19^tm2.1Culp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199625
• Parent Cell Line: CMTI-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed PGKneo selection cassette deleted exons 20-24 of the gene and a STOP cassette was inserted immediately downstream of the 3rd loxP site. (J:199625)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Muc19 Mutation: 41 strains or lines available

References

• Original: J:199625 Das B, et al., The sld genetic defect: two intronic CA repeats promote insertion of the subsequent intron and mRNA decay. J Biol Chem. 2013 May 24;288(21):14742-55
• All: 3 reference(s)