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Nup35Tg(Tyr)2383D-1a1a2Ove
Transgenic Allele Detail
Summary
Symbol: Nup35Tg(Tyr)2383D-1a1a2Ove
Name: nucleoporin 35; transgene insertion 2383D-1a1a2, Paul Overbeek
MGI ID: MGI:5467995
Gene: Nup35  Location: Chr2:80469156-80490415 bp, + strand  Genetic Position: Chr2, 48.31 cM
Alliance: Nup35Tg(Tyr)2383D-1a1a2Ove page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe Tyrosinase minigene is composed of the mouse Tyr enhancer region (623 bp), promoter region (657 bp), and 1566 bp cDNA sequence (including the stop codon). The Tyro minigene is followed by an internal ribosome entry site (IRES) ending with ATGs in all three reading frames (3xATG), an artificial splice donor sequence, and a loxP site. Using inverse PCR analysis, the lentiviral integration site was identified in intron 7 of the nucleoporin 35 gene (Nup35) on chromosome 2 . The 3'-LTR is linked to the (+) strand of DNA at position 80,496,320 bp [NCB137/mm9; 3'-80,496,320(+)]. (J:94077)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nup35 Mutation:  32 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory