Ngdn^{Tg(Tyr)2397E-1a3Ove}
Transgenic Allele Detail

Summary

• Symbol: Ngdn^{Tg(Tyr)2397E-1a3Ove}
• Name: neuroguidin, EIF4E binding protein; transgene insertion 2397E-1a3, Paul Overbeek
• MGI ID: MGI:5467994
• Gene: Ngdn Location: Chr14:55252911-55261594 bp, + strand Genetic Position: Chr14, 28.03 cM, cytoband C1
• Alliance: Ngdn^{Tg(Tyr)2397E-1a3Ove} page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The Tyrosinase minigene is composed of the mouse Tyr enhancer region (623 bp), promoter region (657 bp), and 1566 bp cDNA sequence (including the stop codon). The minigene is followed by an internal ribosome entry site (IRES) ending with ATGs in all three reading frames (3xATG), an artificial splice donor sequence, and a loxP site. Using inverse PCR analysis, the lentiviral integration site was identified in intron 3 of the neuroguidin EIF4E binding protein gene (Ngdn) on chromosome 14. The 3'-LTR is linked to the (-) strand of DNA at position 55,639,729 bp [NCB137/mm9; 3'-55,639,729(-)]. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ngdn Mutation: 19 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)