Tg(Rho-Sag*)Tr12Seva
Transgene Detail

Summary

• Symbol: Tg(Rho-Sag*)Tr12Seva
• Name: transgene insertion Tr12, Vsevolod Gurevich
• MGI ID: MGI:5467811
• Transgene: Tg(Rho-Sag*)Tr12Seva Location: unknown
• Alliance: Tg(Rho-Sag*)Tr12Seva page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rho-Sag*)Tr12Seva expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sag (MGI:98227)

• Mutation details: The transgenic construct contains three amino acid substitutions (Leu374Ala, Val375Ala, and Phe376Ala) introduced into the mouse retinal S-antigen (arrestin; (GenBank M24086)) coding sequence under the direction of the mouse rod opsin promoter. (J:99855)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:170273 Song X, et al., Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health. Neuroscience. 2011 Feb 3;174:37-49
• All: 5 reference(s)