Mirc16^tm1.1Czc
Targeted Allele Detail

Summary

• Symbol: Mirc16^tm1.1Czc
• Name: microRNA cluster 16, including Mir181d through Mir181c; targeted mutation 1.1, Chang-Zheng Chen
• MGI ID: MGI:5467794
• Synonyms: mir181cd^f
• Gene: Mirc16 Location: Chr8:84905345-84905590 bp Genetic Position: Chr8, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188125
• Parent Cell Line: CGR8 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: LoxP sites were inserted at least 125 bp upstream and downstream of the cluster. Flp-mediated recombination removed an FRT-flanked neo cassette. (J:188125)

Generation of the Mirc16^tm1.1Czc allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc16 Mutation: 1 strain or line available

References

• Original: J:188125 Fragoso R, et al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet. 2012 Aug;8(8):e1002855
• All: 1 reference(s)