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Ric8atm1.1Zhua
Targeted Allele Detail
Nomenclature
Symbol: Ric8atm1.1Zhua
Name: RIC8 guanine nucleotide exchange factor A; targeted mutation 1.1, Zhen Zhuang
MGI ID: MGI:5467414
Gene: Ric8a  Location: Chr7:140857397-140863731 bp, + strand  Genetic Position: Chr7, 86.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191222
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 2 through 4 were floxed. Flp-mediated recombination removed the floxed neomycin resistance cassette. (J:191222, J:241849)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ric8a Mutation:  25 strains or lines available
References
Original:  J:191222 Ma S, et al., Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci. 2012 Oct 24;32(43):14979-93
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory