Pycard^tm1Ayaz
Targeted Allele Detail

Summary

• Symbol: Pycard^tm1Ayaz
• Name: PYD and CARD domain containing; targeted mutation 1, Amir S Yazdi
• MGI ID: MGI:5467340
• Synonyms: ASC^f
• Gene: Pycard Location: Chr7:127590545-127593039 bp, - strand Genetic Position: Chr7, 69.88 cM, cytoband F4
• Alliance: Pycard^tm1Ayaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191239
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:191239)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pycard Mutation: 13 strains or lines available

References

• Original: J:191239 Drexler SK, et al., Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18384-9
• All: 5 reference(s)