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Targeted Allele Detail
Symbol: Tab2tm2.1Aki
Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2; targeted mutation 2.1, Shizuo Akira
MGI ID: MGI:5464099
Synonyms: TAB2flox
Gene: Tab2  Location: Chr10:7905653-7956230 bp, - strand  Genetic Position: Chr10, 2.56 cM
Germline Transmission:  Earliest citation of germline transmission: J:81816
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsFlanking loxP sites were introduced to the large exon and a floxed neo cassette was inserted into the upstream intron. Cre-mediated recombination removed the neo cassette and left the exon floxed. (J:81816)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tab2 Mutation:  2 strains or lines available
Original:  J:81816 Sanjo H, et al., TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling. Mol Cell Biol. 2003 Feb;23(4):1231-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory