Akap7^tm1Gsm
Targeted Allele Detail

Summary

• Symbol: Akap7^tm1Gsm
• Name: A kinase anchor protein 7; targeted mutation 1, G Stanley Mcknight
• MGI ID: MGI:5451047
• Gene: Akap7 Location: Chr10:25044988-25175115 bp, - strand Genetic Position: Chr10, 12.26 cM, cytoband A3
• Alliance: Akap7^tm1Gsm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190389
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 7 and a loxP site was inserted in the 3' untranslated region. (J:190389)

Generation of the Akap7^tm1Gsm and Akap7^tm1.1Gsm alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akap7 Mutation: 30 strains or lines available

References

• Original: J:190389 Jones BW, et al., Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17099-104
• All: 2 reference(s)