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Targeted Allele Detail
Symbol: Abcg1tm1Tall
Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Alan Tall
MGI ID: MGI:5450880
Synonyms: Abcg1fl
Gene: Abcg1  Location: Chr17:31276668-31336958 bp, + strand  Genetic Position: Chr17, 15.8 cM, cytoband A2-B
Germline Transmission:  Earliest citation of germline transmission: J:190966
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to insert a single frt site and a single loxP site upstream of exon 3, and a loxP-flanked neomycin resistance (neo) cassette downstream of exon 3. (J:190966)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Abcg1 Mutation:  35 strains or lines available
Original:  J:190966 Westerterp M, et al., Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways. Cell Stem Cell. 2012 Aug 3;11(2):195-206
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory