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Cyp2s1tm1Ding
Targeted Allele Detail
Nomenclature
Symbol: Cyp2s1tm1Ding
Name: cytochrome P450, family 2, subfamily s, polypeptide 1; targeted mutation 1, Xinxin Ding
MGI ID: MGI:5449902
Gene: Cyp2s1  Location: Chr7:25802469-25816525 bp, - strand  Genetic Position: Chr7, 14.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190445
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3 was replaced with a hygromycin resistance gene cassette and loxP site via homologous recombination. (J:190445)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp2s1 Mutation:  2 strains or lines available
References
Original:  J:190445 Wei Y, et al., Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model. Drug Metab Dispos. 2013 Jan;41(1):132-40
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory