Fras1^tm1.1Pjsc
Targeted Allele Detail

Summary

• Symbol: Fras1^tm1.1Pjsc
• Name: Fraser extracellular matrix complex subunit 1; targeted mutation 1.1, Peter J Scambler
• MGI ID: MGI:5449386
• Synonyms: Fras1^fl, Fras1^tm1UCL
• Gene: Fras1 Location: Chr5:96521814-96932587 bp, + strand Genetic Position: Chr5, 47.29 cM
• Alliance: Fras1^tm1.1Pjsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190659
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:190659)

Generation of the Fras1^tm1.1Pjsc and Fras1^tm1.2Pjsc alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Fras1 Mutation: 216 strains or lines available

References

• Original: J:190659 Pitera JE, et al., Generation of mice with a conditional null fraser syndrome 1 (Fras1) allele. Genesis. 2012 Dec;50(12):892-8
• All: 1 reference(s)