Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli
• Name: transgene insertion, Jack A Elias
• MGI ID: MGI:5447949
• Synonyms: Chit1 Tg
• Transgene: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli Location: unknown
• Alliance: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Transactivator)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The mouse promoter drives lung-specific expression of the tetracycline reverse transactivator (rtTA), and the tetracycline promoter element drives inducible expression of the human cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:189872)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:189872 Lee CG, et al., Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-beta1 signaling. J Immunol. 2012 Sep 1;189(5):2635-44
• All: 1 reference(s)