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Serpinb3atm1Gsil
Targeted Allele Detail
Nomenclature
Symbol: Serpinb3atm1Gsil
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; targeted mutation 1, Gary A Silverman
MGI ID: MGI:5447741
Gene: Serpinb3a  Location: Chr1:106973317-106980033 bp, - strand  Genetic Position: Chr1, 50.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189949
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector containing a NEO cassette replaced most of exon 8. RT-PCR confirmed the absence of transcript expression. (J:189949)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Serpinb3a Mutation:  21 strains or lines available
References
Original:  J:189949 Sivaprasad U, et al., A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma. J Allergy Clin Immunol. 2011 Jan;127(1):254-61, 261.e1-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory