About   Help   FAQ
Tg(Cdh5-tTA)D4Lbjn
Transgene Detail
Summary
Symbol: Tg(Cdh5-tTA)D4Lbjn
Name: transgene insertion D4, Laura E Benjamin
MGI ID: MGI:5447033
Synonyms: VEcad-tTA
Transgene: Tg(Cdh5-tTA)D4Lbjn  Location: unknown  
Alliance: Tg(Cdh5-tTA)D4Lbjn page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe Cdh5 (VE-cadherin) promoter was inserted upstream of the tetracycline-regulated transcriptional activator (tTA) gene. Four founder lines were tested and found to show similar performance. Lines D4 and D5 were generated. (J:95750)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:189131 Kobayashi H, et al., Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol. 2010 Nov;12(11):1046-56
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/06/2026
MGI 6.24
The Jackson Laboratory