Tg(tetO-RNAi:Vegfa)#Atuf
Transgene Detail

Summary

• Symbol: Tg(tetO-RNAi:Vegfa)#Atuf
• Name: transgene insertion, Alda Tufro
• MGI ID: MGI:5446890
• Synonyms: tet-O-siVEGF
• Transgene: Tg(tetO-RNAi:Vegfa)#Atuf Location: unknown
• Alliance: Tg(tetO-RNAi:Vegfa)#Atuf page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inducible, Knockdown)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-RNAi:Vegfa)#Atuf involves 1 genes/genome features (Vegfa) View all
• Mutation details: The modified tetracycline response element drives inducible expression of a double stranded short-hairpin RNA targeting Vegfa. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:189626)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:189626 Veron D, et al., Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. PLoS One. 2012;7(7):e40589
• All: 2 reference(s)