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Glp2rtm1.1Xfg
Targeted Allele Detail
Nomenclature
Symbol: Glp2rtm1.1Xfg
Name: glucagon-like peptide 2 receptor; targeted mutation 1.1, Xinfu Guan
MGI ID: MGI:5446802
Synonyms: Glp2rfl
Gene: Glp2r  Location: Chr11:67663784-67771153 bp, - strand  Genetic Position: Chr11, 41.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189593
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT flanked neo cassette and loxP site were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:189593)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glp2r Mutation:  4 strains or lines available
References
Original:  J:189593 Guan X, et al., GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility. Am J Physiol Endocrinol Metab. 2012 Oct 1;303(7):E853-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory