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Tg(Fabp4-SREBF1)#Dajl
Transgene Detail
Nomenclature
Symbol: Tg(Fabp4-SREBF1)#Dajl
Name: transgene insertion, David J Lloyd
MGI ID: MGI:5446499
Synonyms: aP2-nSrebp1c lipodystrophy Tg
Transgene: Tg(Fabp4-SREBF1)#Dajl  Location: unknown  
Lipodystrophy in Tg(Fabp4-SREBF1)#Dajl/0 males

Show the 1 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Fabp4-SREBF1)#Dajl expresses 1 gene
 
Mutation detailsA 5.4 Kb genomic fragment containing the mouse Fabp4 promoter/enhancer elements drives expression of a 1450 bp cDNA encompassing the mature human SREBF1 (residues 1-436). Transgene expression is detected in adipose tissues. (J:189510)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:189510 Veniant MM, et al., FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. PLoS One. 2012;7(7):e40164
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory