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Timp3tm1.1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Timp3tm1.1(KOMP)Vlcg
Name: tissue inhibitor of metalloproteinase 3; targeted mutation 1.1, Velocigene
MGI ID: MGI:5445932
Gene: Timp3  Location: Chr10:86300372-86349506 bp, + strand  Genetic Position: Chr10, 42.83 cM, cytoband C1-D1
Mutation
origin
Mutant Cell Line:  17200A-E2
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 37594bp between positions 85763602-85801195 of Chromosome 10 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 50 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Timp3 Mutation:  9 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory