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Tg(H2-Kb-Jak2*V617F)2Shmd
Transgene Detail
Nomenclature
Symbol: Tg(H2-Kb-Jak2*V617F)2Shmd
Name: transgene insertion 2, Kazuya Shimoda
MGI ID: MGI:5444028
Synonyms: JAK2 V617F
Transgene: Tg(H2-Kb-Jak2*V617F)2Shmd  Location: unknown  Genetic Position: Chr7, Syntenic
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-Kb-Jak2*V617F)2Shmd expresses 1 gene
 
Mutation detailsThis transgene consists of murine Jak2 with a phenylalanine for valine substitution at residue 617 under the control of the H-2Kb promoter. The transgene integrated between Mef2a and Lrrc28 in this line. (J:130189)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:130189 Shide K, et al., Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F. Leukemia. 2008 Jan;22(1):87-95
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory