Tg(AMELX-EGFP/RHOA*T19N)13Gibs
Transgene Detail

Summary

• Symbol: Tg(AMELX-EGFP/RHOA*T19N)13Gibs
• Name: transgene insertion 13, Carolyn Gibson
• MGI ID: MGI:5443834
• Synonyms: TgAmelxEGFP-RhoA^DN-13, Tg(Amelx-EGFPRhoA-DN)13Gibs
• Transgene: Tg(AMELX-EGFP/RHOA*T19N)13Gibs Location: unknown
• Alliance: Tg(AMELX-EGFP/RHOA*T19N)13Gibs page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Dominant negative, Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(AMELX-EGFP/RHOA*T19N)13Gibs expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  RHOA (387)

  Rhoa	(MGI:1096342)

• Mutation details: The bovine promoter drives ameloblast-specific expression of an EGFP and dominant negative human RHOA (T19N) fusion. Three lines were generated (8, 2, and 13 with low, intermediate and high expression, respectively). (J:188913)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:188913 Li Y, et al., Dental enamel structure is altered by expression of dominant negative RhoA in ameloblasts. Cells Tissues Organs. 2011;194(2-4):227-31
• All: 3 reference(s)