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Mgat5btm1.1Itl
Targeted Allele Detail
Nomenclature
Symbol: Mgat5btm1.1Itl
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B; targeted mutation 1.1, inGenious Targeting Laboratory
MGI ID: MGI:5442815
Synonyms: GnT-Vbdfl
Gene: Mgat5b  Location: Chr11:116918863-116986948 bp, + strand  Genetic Position: Chr11, 81.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188930
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 6. An FRT- and loxP flanked neo cassette was inserted downstream of exon 6. Cre-mediated recombination removed exon 6 and the neo cassette. (J:188930)
Generation of the Mgat5btm1Itl and Mgat5btm1.1Itl alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mgat5b Mutation:  52 strains or lines available
References
Original:  J:188930 Lee JK, et al., Developmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-V. J Biol Chem. 2012 Aug 17;287(34):28526-36
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory