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Rgs16tm1.1Drue
Targeted Allele Detail
Nomenclature
Symbol: Rgs16tm1.1Drue
Name: regulator of G-protein signaling 16; targeted mutation 1.1, Kirk Druey
MGI ID: MGI:5442790
Gene: Rgs16  Location: Chr1:153740353-153745468 bp, + strand  Genetic Position: Chr1, 65.43 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188966
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 2 through 4 and the neo cassette. (J:188966)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs16 Mutation:  3 strains or lines available
References
Original:  J:188966 Shankar SP, et al., RGS16 attenuates pulmonary Th2/Th17 inflammatory responses. J Immunol. 2012 Jun 15;188(12):6347-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory