Tg(Adam12-cre,-EGFP)1Lpe
Transgene Detail

Summary

• Symbol: Tg(Adam12-cre,-EGFP)1Lpe
• Name: transgene insertion 1, Lucie Peduto
• MGI ID: MGI:5442695
• Synonyms: Adam12-cre-ires-egfp^TG, M12-CIG
• Transgene: Tg(Adam12-cre,-EGFP)1Lpe Location: unknown
• Alliance: Tg(Adam12-cre,-EGFP)1Lpe page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Adam12-cre,-EGFP)1Lpe expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Adam12

• Mutation details: A cre-ires-EGFP coding sequence, including a polyA sequence was inserted into exon 1 of the Adam12 gene in a 200 kb BAC by homologous recombination. The sequence replaced the endogenous ATG translation start codon. The modified BAC was used to generate transgenic founders. Line information is not available. (J:188912)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Adam12 (species not specified) Summary of all recombinase alleles driven by Adam12.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:188912 Dulauroy S, et al., Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med. 2012 Aug;18(8):1262-70
• All: 2 reference(s)