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Zfp36tm1.1Xen
Targeted Allele Detail
Nomenclature
Symbol: Zfp36tm1.1Xen
Name: zinc finger protein 36; targeted mutation 1.1, Taconic Biosciences
MGI ID: MGI:5441582
Synonyms: Zfp36flox
Gene: Zfp36  Location: Chr7:28376784-28379228 bp, - strand  Genetic Position: Chr7, 16.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188677
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of the exon 2. An additional loxP site was inserted downstream of the exon 2. Cre-mediated recombination removed the neo cassette and left exon 2 floxed. (J:188677)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfp36 Mutation:  11 strains or lines available
References
Original:  J:188677 Qiu LQ, et al., Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype. J Immunol. 2012 May 15;188(10):5150-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory