Acvr1btm1.2Pbe
Targeted Allele Detail
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Symbol: |
Acvr1btm1.2Pbe |
Name: |
activin A receptor, type 1B; targeted mutation 1.2, Philippe Bertolino |
MGI ID: |
MGI:5441234 |
Synonyms: |
Acvr1b-Floxed, Acvr1bFx |
Gene: |
Acvr1b Location: Chr15:101071953-101111565 bp, + strand Genetic Position: Chr15, 56.48 cM
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Alliance: |
Acvr1btm1.2Pbe page
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Germline Transmission: |
Earliest citation of germline transmission:
J:188629
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Parent Cell Line: |
CK35 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An FRT flanked neo cassette and loxP site were inserted in intron 4. An additional loxP was inserted into intron 6. Flp-mediated recombination removed the neo cassette and left exons 5 and 6 floxed.
(J:188629)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Acvr1b Mutation: |
36 strains or lines available
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Original: |
J:188629 Ripoche D, et al., Generation of a conditional mouse model to target Acvr1b disruption in adult tissues. Genesis. 2013 Feb;51(2):120-7 |
All: |
3 reference(s) |
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