Sgpl1tm1c(KOMP)Saba
Targeted Allele Detail
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Symbol: |
Sgpl1tm1c(KOMP)Saba |
Name: |
sphingosine phosphate lyase 1; targeted mutation 1c, Julie D Saba |
MGI ID: |
MGI:5440318 |
Gene: |
Sgpl1 Location: Chr10:60934421-60983463 bp, - strand Genetic Position: Chr10, 32.14 cM
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Alliance: |
Sgpl1tm1c(KOMP)Saba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:187619
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A targeting vector directed to the Sgpl1 gene was created by the KOMP project. A promoterless beta geo cassette flanked by FRT sites and containing loxP sites was inserted 5' of exon 10 while an additional loxP site was inserted in intron 12. The targeting cassette was then excised leaving exons 10-12 which encode the enzyme cofactor binding site flanked by loxP sites.
(J:187619)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sgpl1 Mutation: |
33 strains or lines available
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Original: |
J:187619 Borowsky AD, et al., Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. J Lipid Res. 2012 Sep;53(9):1920-31 |
All: |
5 reference(s) |
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