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Sgpl1tm1a(KOMP)Saba
Targeted Allele Detail
Summary
Symbol: Sgpl1tm1a(KOMP)Saba
Name: sphingosine phosphate lyase 1; targeted mutation 1a, Julie D Saba
MGI ID: MGI:5440317
Gene: Sgpl1  Location: Chr10:60934421-60983463 bp, - strand  Genetic Position: Chr10, 32.14 cM
Alliance: Sgpl1tm1a(KOMP)Saba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187619
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector directed to the Sgpl1 gene was created by the KOMP project. A promoterless beta geo cassette flanked by FRT sites and containing loxP sites was inserted 5' of exon 10 while an additional loxP site was inserted in intron 12. (J:187619)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sgpl1 Mutation:  33 strains or lines available
References
Original:  J:187619 Borowsky AD, et al., Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. J Lipid Res. 2012 Sep;53(9):1920-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory