Rif1^tm3.1Sbcd
Targeted Allele Detail

Summary

• Symbol: Rif1^tm3.1Sbcd
• Name: replication timing regulatory factor 1; targeted mutation 3.1, Sara B C Buonomo
• MGI ID: MGI:5439959
• Synonyms: Rif1^FH
• Gene: Rif1 Location: Chr2:51962844-52012395 bp, + strand Genetic Position: Chr2, 29.98 cM
• Alliance: Rif1^tm3.1Sbcd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188030
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A FLAG-tag was added to the 5' end of exon 2, replacing the Rif1 start codon. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of the modified exon 2. (J:188030)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rif1 Mutation: 172 strains or lines available

References

• Original: J:188030 Cornacchia D, et al., Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J. 2012 Jul 31;31(18):3678-90
• All: 2 reference(s)