Armc8^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Armc8^tm1.1Geno
• Name: armadillo repeat containing 8; targeted mutation 1.1, Genoway
• MGI ID: MGI:5439655
• Synonyms: 3xFlag.ARMC8
• Gene: Armc8 Location: Chr9:99360425-99450952 bp, - strand Genetic Position: Chr9, 51.74 cM, cytoband F1
• Alliance: Armc8^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187380
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 1, a 3X Flag tag was added after the initiation codon and a loxP site was inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:187380)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Armc8 Mutation: 45 strains or lines available

References

• Original: J:187380 Dey A, et al., Loss of the tumor suppressor BAP1 causes myeloid transformation. Science. 2012 Sep 21;337(6101):1541-6
• All: 2 reference(s)