Bap1^tm1.1Vmd
Targeted Allele Detail

Summary

• Symbol: Bap1^tm1.1Vmd
• Name: Brca1 associated protein 1; targeted mutation 1.1, Vishva M Dixit
• MGI ID: MGI:5439654
• Synonyms: Bap1.3xFlag
• Gene: Bap1 Location: Chr14:30973407-30981901 bp, + strand Genetic Position: Chr14, 19.09 cM
• Alliance: Bap1^tm1.1Vmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187380
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette was inserted in intron 16 and a 3xFlag tag was added to the end of the coding region before the stop codon exon 17 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:187380)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bap1 Mutation: 37 strains or lines available

References

• Original: J:187380 Dey A, et al., Loss of the tumor suppressor BAP1 causes myeloid transformation. Science. 2012 Sep 21;337(6101):1541-6
• All: 2 reference(s)