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Bap1tm1.1Geno
Targeted Allele Detail
Nomenclature
Symbol: Bap1tm1.1Geno
Name: Brca1 associated protein 1; targeted mutation 1.1, Genoway
MGI ID: MGI:5439652
Synonyms: Bap1fl
Gene: Bap1  Location: Chr14:31251454-31259930 bp, + strand  Genetic Position: Chr14, 19.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187380
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and FRT flanked neo cassette were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:187380)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bap1 Mutation:  15 strains or lines available
References
Original:  J:187380 Dey A, et al., Loss of the tumor suppressor BAP1 causes myeloid transformation. Science. 2012 Sep 21;337(6101):1541-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory