Del(3Gbp2-ps-Gbp5)1Ktak
Targeted Allele Detail

Summary

• Symbol: Del(3Gbp2-ps-Gbp5)1Ktak
• Name: deletion, Chr 3, Kiyoshi Takeda 1
• MGI ID: MGI:5438974
• Synonyms: Del1Ktak, Gbp^chr3, GBPchr3^-
• Gene: Del(3Gbp2-ps-Gbp5)1Ktak Location: unknown Genetic Position: Chr3, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187397
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(3Gbp2-ps-Gbp5)1Ktak involves 7 genes/genome features (Gbp5, Gbp7, Gbp3 ...) View all
• Mutation details: Cre-mediated recombination of Gbp-ps2^tm1.1Ktak and Gbp5^tm1Ktak in cis removed 173 kb encompassing Gbp2-ps, Gbp2, Gbp1, Gbp3, Gbp7 and Gbp5. RT-PCR confirmed the absence of transcript expression from these genes. (J:187397)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(3Gbp2-ps-Gbp5)1Ktak Mutation: 0 strains or lines available

References

• Original: J:187397 Yamamoto M, et al., A Cluster of Interferon-gamma-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii. Immunity. 2012 Aug 24;37(2):302-313
• All: 20 reference(s)