Gbp5^tm1Ktak
Targeted Allele Detail

Summary

• Symbol: Gbp5^tm1Ktak
• Name: guanylate binding protein 5; targeted mutation 1, Kiyoshi Takeda
• MGI ID: MGI:5438972
• Gene: Gbp5 Location: Chr3:142202695-142228105 bp, + strand Genetic Position: Chr3, 66.69 cM
• Alliance: Gbp5^tm1Ktak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187397
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 2 and 3 were replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:187397)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gbp5 Mutation: 37 strains or lines available

Notes

This allele was originally generated in ES cells containing Gbp-ps2^tm1.1Ktak.

References

• Original: J:187397 Yamamoto M, et al., A Cluster of Interferon-gamma-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii. Immunity. 2012 Aug 24;37(2):302-313
• All: 2 reference(s)