Id2^tm1.1Zhu
Targeted Allele Detail

Summary

• Symbol: Id2^tm1.1Zhu
• Name: inhibitor of DNA binding 2; targeted mutation 1.1, Yuan Zhuang
• MGI ID: MGI:5437253
• Synonyms: Id2^hCD5
• Gene: Id2 Location: Chr12:25143798-25146091 bp, - strand Genetic Position: Chr12, 8.57 cM, cytoband B
• Alliance: Id2^tm1.1Zhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187334
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES sequence, a tailess human CD5 cDNA and floxed neo cassette were inserted into the 3' untranslated region in exon 3. Cre-mediated recombination removed the neo cassette. (J:187334)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Id2 Mutation: 17 strains or lines available

References

• Original: J:187334 Jones-Mason ME, et al., E protein transcription factors are required for the development of CD4(+) lineage T cells. Immunity. 2012 Mar 23;36(3):348-61
• All: 4 reference(s)