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Targeted Allele Detail
Symbol: Sox7tm1.1Dsco
Name: SRY (sex determining region Y)-box 7; targeted mutation 1.1, Daryl A Scott
MGI ID: MGI:5437221
Gene: Sox7  Location: Chr14:63943706-63950732 bp, + strand  Genetic Position: Chr14, 33.34 cM, cytoband C3
Germline Transmission:  Earliest citation of germline transmission: J:187416
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed exon 2 and the neo cassette. (J:187416)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox7 Mutation:  11 strains or lines available
Original:  J:187416 Wat MJ, et al., Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1. Hum Mol Genet. 2012 Sep 15;21(18):4115-25
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory