Pink1^tm1Wrst
Targeted Allele Detail

Summary

• Symbol: Pink1^tm1Wrst
• Name: PTEN induced putative kinase 1; targeted mutation 1, Wolfgang Wurst
• MGI ID: MGI:5436307
• Synonyms: Pink1^l
• Gene: Pink1 Location: Chr4:138040720-138053618 bp, - strand Genetic Position: Chr4, 70.14 cM
• Alliance: Pink1^tm1Wrst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183290
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and FRt flanked neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 3 via homologous recombination. (J:183290)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pink1 Mutation: 42 strains or lines available

References

• Original: J:183290 Glasl L, et al., Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb. Exp Neurol. 2012 May;235(1):214-27
• All: 2 reference(s)