Tg(KRT10-Igf2r*)KippsGfc
Transgene Detail

Summary

• Symbol: Tg(KRT10-Igf2r*)KippsGfc
• Name: transgene insertion Kipps, Christopher Graham
• MGI ID: MGI:5436057
• Synonyms: K10s(delta)Igf2r/Kipps
• Transgene: Tg(KRT10-Igf2r*)KippsGfc Location: unknown
• Alliance: Tg(KRT10-Igf2r*)KippsGfc page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT10-Igf2r*)KippsGfc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igf2r (MGI:96435)

• Mutation details: The transgene expresses a truncated, soluble form of Igf2r cDNA from the bovine homolog of the keratin-10 promoter. Seven founders were identified. The Kipps line exhibits the highest transgene expression. (J:146732)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:146732 Zaina S, et al., Local reduction of organ size in transgenic mice expressing a soluble insulin-like growth factor II/mannose-6-phosphate receptor. Endocrinology. 1998 Sep;139(9):3886-95
• All: 3 reference(s)