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Targeted Allele Detail
Symbol: Khktm2.1Dtb
Name: ketohexokinase; targeted mutation 2.1, David T Bonthron
MGI ID: MGI:5435942
Synonyms: Khk-Ntm1.1Ls
Gene: Khk  Location: Chr5:30921436-30931248 bp, + strand  Genetic Position: Chr5, 16.9 cM
Germline Transmission:  Earliest citation of germline transmission: J:169366
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA stop codon was introduced into exon 3a preventing the production of the A transcript. A floxed neo cassette was inserted upstream of the modified exon 3a. Exons 4 through 6 and part of 7 were deleted, preventing the expression of the C splice variant. Cre-mediated recombination removed the neo cassette. (J:169366)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Khk Mutation:  13 strains or lines available
Original:  J:169366 MouseBookTM, Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory