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Fktntm1Kcam
Targeted Allele Detail
Nomenclature
Symbol: Fktntm1Kcam
Name: fukutin; targeted mutation 1, Kevin P Campbell
MGI ID: MGI:5435571
Gene: Fktn  Location: Chr4:53713998-53765785 bp, + strand  Genetic Position: Chr4, 28.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187144
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and an FRT flanked neo selection cassette were inserted upstream of exon 2 while a second loxP site was inserted downstream. (J:187144)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fktn Mutation:  17 strains or lines available
References
Original:  J:187144 Beedle AM, et al., Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy. J Clin Invest. 2012 Sep 4;122(9):3330-42
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory